work packages

EXPANSE is a five-year European research project that focuses on the urban exposome and involves 20 academic and non-academic partners located in 14 European countries and the USA.

The main aim of EXPANSE is to address one of the most pertinent questions for urban planners, policy makers, and inhabitants in Europe: “How to maximize one’s health in a modern urban environment?” To this end the EXPANSE project has been structured around seven Work Packages (WP’s).

OVERALL STRUCTURE

Divided into seven main Work Packages.

 

WP 1
EXTERNAL EXPOSOME

Lead partner: SWISS TPH

Our goal is to comprehensively characterise the External Urban Exposome, including the food, lifestyle, social, built, and physico-chemical environments. We will improve methodologies and analytical tools to enable individualised assessments of the External Urban Exposome.

WP 2
INTERNAL EXPOSME

Lead partner: Helmholtz Research Centre for Environmental Health

Our goal is to comprehensively characterise the Internal Urban Exposome, which includes biological responses to cumulative exposures. We will integrate the wealth of OMICS data within the cohorts, and generate new Internal Exposome data from ultra-high-resolution mass spectrometry.

WP3
EXPOSOME-HEALTH

Lead partner: Karolinska Institutet

Our goal is to decrease the proportion of unexplained Cardio-Metabolic and Pulmonary Disease (CMPD) risk in urban populations and to gain insights into mediating biological mechanisms and causality. To do so we will develop tools to link External and Internal Urban Exposome measures to CMPD.

WP 4
INTERVENTIONS

Lead partner: ISGlobal

Our goal is to comprehensively characterise the External Urban Exposome, including the food, lifestyle, social, built, and physico-chemical environments. We will improve methodologies and analytical tools to enable individualised assessments of the External Urban Exposome.

WP 5
METHODS

Lead partner: Imperial College London

Our goal is to remove methodological bottlenecks hampering the successful exploration of the Urban Exposome and its possible health impact by extending established techniques and developing novel statistical approaches.

WP6
TOOLBOX

Lead partner: Utrecht University

Our goal is to create a long-term sustainable toolbox and infrastructure that can be used to generate knowledge on the Urban Exposome and the translation of this knowledge into actionable information for citizens, public sector policy makers, and private sector companies.

WP 7
STAKEHOLDER INTERACTION

Lead partner: University of Tartu

We aim to closely engage our targeted user-stakeholders in the design and development of the Toolbox as described in Objective 6 and provide access to the Exposome Toolbox

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BACKGROUND

URBAN EXPOSOME

RESEARCH

ETHICS

NEWS & EVENTS

Contact us

Yalelaan 2
3584 CM Utrecht
The Netherlands

030 253 9534
exposome.office@uu.nl

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